Search results for "Phosphate buffered saline"

showing 6 items of 6 documents

The excellent biocompatibility and negligible immune response of the titanium heterometallic MOF MUV-10

2021

The Ti-Ca heterometallic MOF MUV-10 exhibits good dispersibility in phosphate buffer and low phosphate-induced degradation in comparison to other MOF systems. It induces no cytotoxicity towards cells of the immune system and no inmune response, making it an attractive candidate for biomedical applications and demonstrating its safe use for other applications.

BiocompatibilityBiomedical Engineeringchemistry.chemical_elementBiocompatible Materials02 engineering and technology010402 general chemistry01 natural sciencesMiceImmune systemMaterials TestingAnimalsHumansGeneral Materials ScienceParticle SizeCytotoxicityMetal-Organic FrameworksTitaniumfungiPhosphate buffered salineImmunityGeneral ChemistryGeneral Medicine021001 nanoscience & nanotechnologyCombinatorial chemistry0104 chemical scienceschemistryDegradation (geology)Calcium0210 nano-technologyTitaniumJournal of Materials Chemistry B
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Probing the self-assembly and stability of oligohistidine based rod-like micelles by aggregation induced luminescence.

2016

OA hybrid The synthesis and self-assembly of a new C2-symmetric oligohistidine amphiphile equipped with an aggregation induced emission luminophore is reported. We observe the formation of highly stable and ordered rod-like micelles in phosphate buffered saline, with a critical aggregation concentration below 200 nM. Aggregation induced emission of the luminophore confirms the high stability of the anisotropic assemblies in serum.

LuminescenceChemistryOrganic ChemistryPhosphate buffered salineAnalytical chemistryChemie02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesBiochemistryMicelle0104 chemical scienceschemistry.chemical_compoundAmphiphileBiophysicsLuminophoreHistidineParticle sizePhysical and Theoretical ChemistryAggregation-induced emissionParticle Size0210 nano-technologyLuminescenceMicellesOrganicbiomolecular chemistry
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The LepR-mediated leptin transport across brain barriers controls food reward

2018

Objective Leptin is a key hormone in the control of appetite and body weight. Predominantly produced by white adipose tissue, it acts on the brain to inhibit homeostatic feeding and food reward. Leptin has free access to circumventricular organs, such as the median eminence, but entry into other brain centers is restricted by the blood–brain and blood–CSF barriers. So far, it is unknown for which of its central effects leptin has to penetrate brain barriers. In addition, the mechanisms mediating the transport across barriers are unclear although high expression in brain barriers suggests an important role of the leptin receptor (LepR). Methods We selectively deleted LepR in brain endothelia…

Male0301 basic medicineLeptinHFD high-fat dietEndothelial cellsWhite adipose tissueCSF cerebrospinal fluidMice0302 clinical medicineCPP conditioned place preferenceBBB blood–brain barrierCells Culturedmedia_commonLeptindigestive oral and skin physiologyi.p. intraperitonealmedicine.anatomical_structureLepRBlood-Brain BarrierBlood–brain barrier; Endothelial cells; LepR; Leptin; Obesity; RewardMedian eminenceqPCR quantitative polymerase chain reactionReceptors LeptinOriginal ArticleChoroid plexusmedicine.medical_specialtylcsh:Internal medicinemedia_common.quotation_subjectHyperphagiaBiologyBlood–brain barrierVTA ventral tegmental areaBC bottle choice testCapillary PermeabilityBlood–brain barrierARC arcuate nucleus03 medical and health sciencesPBS phosphate buffered salineRewardInternal medicinemedicineAnimalsObesitylcsh:RC31-1245Molecular BiologyCircumventricular organsBlood-Nerve BarrierLeptin receptorNCD normal chow dietAppetiteCell Biology030104 developmental biologyEndocrinologyLepR leptin receptorChoroid PlexusBSA bovine serum albuminPFA paraformaldehyde030217 neurology & neurosurgeryDAPI 4′6-diamidino-2-phenylindoleMolecular Metabolism
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Highly activated screen-printed carbon electrodes by electrochemical treatment with hydrogen peroxide

2018

An easy effective method for the activation of commercial screen-printed carbon electrodes (SPCEs) using H2O2 is presented to enhance sensing performances of carbon ink. Electrochemical activation consists of 25 repetitive voltammetric cycles at 10 mV s−1 using 10 mM H2O2 in phosphate buffer (pH 7). This treatment allowed us to reach a sensitivity of 0.24 ± 0.01 μA μM−1 cm−2 for the electroanalysis of H2O2, which is 140-fold higher than that of untreated SPCEs and 6-fold more than screen-printed platinum electrodes (SPPtEs). Electrode surface properties were characterized by SEM, EIS and XPS. The results revealed atomic level changes at the electrode surface, with the introduction of new ca…

Materials scienceElectrochemical activationchemistry.chemical_element02 engineering and technologyElectrochemistry01 natural scienceslcsh:Chemistrychemistry.chemical_compoundX-ray photoelectron spectroscopyElectrochemistryQuímica FísicaScreen-printed carbon electrodesHydrogen peroxideInkwellSensors010401 analytical chemistryPhosphate buffered saline021001 nanoscience & nanotechnologyHydrogen peroxide0104 chemical scienceslcsh:Industrial electrochemistrylcsh:QD1-999chemistryChemical engineeringElectrode0210 nano-technologyPlatinumCarbonlcsh:TP250-261
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A CEMS-study of the passive layer on iron and steel

1988

From AES, ICEMS, and DCEMS experiments it was concluded that the passive layer formed on steel in a phosphate buffer consists of γ-FeOOH. Its thickness increases from 0.5 to 3.5 nm throughout the passive region. It is covered by noncorrelated layers of a precipitate and an adsorbate.

Nuclear and High Energy PhysicsMaterials sciencePhosphate buffered salineMetallurgyPhysical and Theoretical ChemistryCondensed Matter PhysicsLayer (electronics)Atomic and Molecular Physics and OpticsHyperfine Interactions
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Phytoelectrochemical analysis ofZanthoxylum chiloperone

2016

Introduction An innovative application of the voltammetry of microparticles methodology to characterize the phytochemical composition of extracts of different parts of Zanthoxylum chiloperone var. angustifolium Engl. is described. Objective Characterize the phytochemical composition of extracts of different parts of plants by electrochemical methodologies. Methods The voltammetry of microparticles methodology was applied to alcoholic extracts from leaves, seeds, fruits, roots and stem bark of Zanthoxylum chiloperone. Results In contact with aqueous phosphate buffer, characteristic cathodic signals of its main natural products (canthin-6-one, 5-methoxycanthin-6-one and trans-avicennol) were …

Stem barkPhytochemistrybiologyTraditional medicine010405 organic chemistryChemistryPhosphate buffered salinePlant ScienceGeneral Medicine010402 general chemistrybiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesAnalytical ChemistryComplementary and alternative medicineZanthoxylumPhytochemicalDrug DiscoveryCanthin-6-onePhytochemical compositionMolecular MedicineOrganic chemistryFood SciencePhytochemical Analysis
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